President Muhammadu Buhari made reference to COVID-19 during his meeting with Cyril Ramaphosa, his South African counterpart, on Wednesday.
Daily Trust had reported that Ramaphosa arrived the country on a three-day visit.
The South African leader arrived Nigeria at a time when there was global concern over Omicron COVID variant, which was first reported in South Africa.
Many countries have been shutting their doors against South Africa since Omicron variant was reported in the country.
However, at the Aso Rock meeting, Buhari said he was glad that the 10th Session of Nigeria-South Africa Bi-National Commission (BNC) was holding on schedule despite all the challenges posed by the COVID-19 pandemic.
Nigeria detected three cases of Omicron hours before the arrival of Ramaphosa.
The Nigeria Centre for Disease Control (NCDC) said among the cases were two persons who travelled from South Africa last week.