Watford have sacked manager Quique Sanchez Flores after Saturday’s 2-1 loss to Southampton, saying “ultimately results have dictated our decision”.
Chris Hughton is a possible successor and the Hornets said a replacement will be appointed “imminently”.
Sanchez Flores, who was in charge for the 2015-16 season, was reappointed on 7 September, replacing Javi Gracia.
But he won just one of his 10 league games in charge with Watford bottom of the Premier League.
In an open letter to Watford fans published on the club website, the 54-year-old Spaniard said the club “will always be in my heart”.
Watford have eight points after 14 games and are six points from safety – their worst return at this stage of a Premier League campaign.
Sanchez Flores becomes the the third Premier League boss to be sacked in the past two weeks, following Unai Emery at Arsenal on Friday and Mauricio Pochettino at Tottenham on 19 November.
Watford are in their fifth season back in the Premier League since promotion in May 2015.